Volume 39
Main Index

Issue 01

A Novel Approach to the Efficient Oxygenation of Hydrocarbons under Mild Conditions. Superior Oxo Transfer Selectivity Using Dioxiranes Ruggero Curci, Lucia D'Accolti, and Caterina Fusco pp 1–9 DOI: 10.1021/ar050163y

The Chain-Length Dependence Test Matthew T. Stone, Jennifer M. Heemstra, and Jeffrey S. Moore pp 11–20 DOI: 10.1021/ar0501267

Nonadiabatic Dynamics of Condensed Phase Rate Processes Gabriel Hanna and Raymond Kapral pp 21–27 DOI: 10.1021/ar030281q

Molecular Recognition Imaging and Force Spectroscopy of Single Biomolecules Ferry Kienberger, Andreas Ebner, Hermann J. Gruber, and Peter Hinterdorfer pp 29–36 DOI: 10.1021/ar050084m

Structure−Function Relationships of EcDOS, a Heme-Regulated Phosphodiesterase from Escherichia coli Yukie Sasakura, Tokiko Yoshimura-Suzuki, Hirofumi Kurokawa, and Toru Shimizu pp 37–43 DOI: 10.1021/ar0501525

Designer Zinc Finger Proteins:  Tools for Creating Artificial DNA-Binding Functional Proteins Muthu Dhanasekaran, Shigeru Negi, and Yukio Sugiura pp 45–52 DOI: 10.1021/ar050158u

Benefiting from the Unique Properties of Lanthanide Ions Jean-Claude G. Bünzli pp 53–61 DOI: 10.1021/ar0400894

Issue 02

Computational and Theoretical Chemistry Emily A. Carter, Peter J. Rossky pp 71–72 DOI: 10.1021/ar050190o

Metadynamics as a Tool for Exploring Free Energy Landscapes of Chemical Reactions Bernd Ensing, Marco De Vivo, Zhiwei Liu, Preston Moore, and Michael L. Klein pp 73–81 DOI: 10.1021/ar040198i

Spin-Flip Equation-of-Motion Coupled-Cluster Electronic Structure Method for a Description of Excited States, Bond Breaking, Diradicals, and Triradicals Anna I. Krylov pp 83–91 DOI: 10.1021/ar0402006

Hydrogen Tunneling and Protein Motion in Enzyme Reactions Sharon Hammes-Schiffer pp 93–100 DOI: 10.1021/ar040199a

Non-Born−Oppenheimer Molecular Dynamics Ahren W. Jasper, Shikha Nangia, Chaoyuan Zhu, and Donald G. Truhlar pp 101–108 DOI: 10.1021/ar040206v

Magnetoresistance of Nanoscale Molecular Devices Oded Hod, Eran Rabani, and Roi Baer pp 109–117 DOI: 10.1021/ar0401909

Insights for Light-Driven Molecular Devices from Ab Initio Multiple Spawning Excited-State Dynamics of Organic and Biological Chromophores Todd J. Martínez pp 119–126 DOI: 10.1021/ar040202q

Guided Gaussian Wave Packets E. J. Heller pp 127–134 DOI: 10.1021/ar040196y

Mechanisms of Protein Assembly:  Lessons from Minimalist Models Yaakov Levy and José N. Onuchic pp 135–142 DOI: 10.1021/ar040204a

Computer Simulation of Proton Solvation and Transport in Aqueous and Biomolecular Systems Gregory A. Voth pp 143–150 DOI: 10.1021/ar0402098

Structure and Dynamics of OH-(aq) Mark E. Tuckerman, Amalendu Chandra, Dominik Marx pp 151–158 DOI: 10.1021/ar040207n

Heterogeneous Reactions Important in Atmospheric Ozone Depletion:  A Theoretical Perspective Roberto Bianco and James T. Hynes pp 159–165 DOI: 10.1021/ar040197q

Catalytic Reduction of Dinitrogen to Ammonia at a Single Molybdenum Center Richard R. Schrock pp 167–167 DOI: 10.1021/ar068000c

Issue 03

Elucidation of Residue-Level Structure and Dynamics of Polypeptides via Isotope-Edited Infrared Spectroscopy Sean M. Decatur pp 169–175 DOI: 10.1021/ar050135f

Solid-State NMR Studies of the Structure, Dynamics, and Assembly of β-Sheet Membrane Peptides and α-Helical Membrane Proteins with Antibiotic Activities Mei Hong pp 176–183 DOI: 10.1021/ar040037e

Computational Studies of the Primary Phototransduction Event in Visual Rhodopsin José A. Gascón, Eduardo M. Sproviero, and Victor S. Batista pp 184–193 DOI: 10.1021/ar050027t

Advances in Nitrogen Transfer Reactions Involving Aziridines Iain D. G. Watson, Lily Yu, and Andrei K. Yudin pp 194–206 DOI: 10.1021/ar050038m

Quantum Chemistry without Wave Functions:  Two-Electron Reduced Density Matrices David A. Mazziotti pp 207–215 DOI: 10.1021/ar050029d

Dynamical Structure of Peptide Molecules Yoshiyuki Kawashima, Tsuyoshi Usami, Nobukimi Ohashi, Richard D. Suenram, Jon T. Hougen, and Eizi Hirota pp 216–220 DOI: 10.1021/ar040310c

Ligand-Modulated Palladium-Catalyzed Aerobic Alcohol Oxidations Matthew S. Sigman and David R. Jensen pp 221–229 DOI: 10.1021/ar040243m

Issue 04

The Chemistry of Life's Origin:  A Carbonaceous Meteorite Perspective Sandra Pizzarello pp 231–237 DOI: 10.1021/ar050049f

Inorganic Nanotubes:  A Novel Platform for Nanofluidics Joshua Goldberger, Rong Fan, and Peidong Yang pp 239–248 DOI: 10.1021/ar040274h

Large-Area Nanoscale Patterning:  Chemistry Meets Fabrication Joel Henzie, Jeremy E. Barton, Christopher L. Stender, and Teri W. Odom pp 249–257 DOI: 10.1021/ar050013n

Stereoelectronic Substituent Effects Henrik Helligsø Jensen and Mikael Bols pp 259–265 DOI: 10.1021/ar050189p

Diazirines:  Carbene Precursors Par Excellence Robert A. Moss pp 267–272 DOI: 10.1021/ar050155h

Toward Improved Catalytic Low-Temperature NOx Removal in Diesel-Powered Vehicles Fredrik Klingstedt, Kalle Arve, Kari Eränen, and Dmitry Yu. Murzin pp 273–282 DOI: 10.1021/ar050185k

Is Competition between Li+ and Mg2+ the Underlying Theme in the Proposed Mechanisms for the Pharmacological Action of Lithium Salts in Bipolar Disorder? Duarte Mota de Freitas, M. Margarida C. A. Castro, and Carlos F. G. C. Geraldes pp 283–291 DOI: 10.1021/ar030197a

Issue 05

Light and Singlet Oxygen in Plant Defense Against Pathogens:  Phototoxic Phenalenone Phytoalexins Cristina Flors and Santi Nonell pp 293–300 DOI: 10.1021/ar0402863

Pentamethylcyclopentadienyl Ruthenium(III) vs Hexamethylbenzene Ruthenium(II) in Sulfur-Centered Reactivity of Their Thioether-Thiolate and Allied Complexes Richard Yee Cheong Shin and Lai Yoong Goh pp 301–313 DOI: 10.1021/ar050077y

Crystals and Crystallinity in Polymeric Materials Paolo Corradini, Finizia Auriemma, and Claudio De Rosa pp 314–323 DOI: 10.1021/ar040288n

New Features in Pentacoordinate Phosphorus Chemistry K. C. Kumara Swamy and N. Satish Kumar pp 324–333 DOI: 10.1021/ar050188x

Fabricating and Controlling Molecular Self-Organization at Solid Surfaces:  Studies by Scanning Tunneling Microscopy Li-Jun Wan pp 334–342 DOI: 10.1021/ar0501929

What Anions Do to N−H-Containing Receptors Valeria Amendola, David Esteban-Gómez, Luigi Fabbrizzi, and Maurizio Licchelli pp 343–353 DOI: 10.1021/ar050195l

The Phomactins. A Novel Group of Terpenoid Platelet Activating Factor Antagonists Related Biogenetically to the Taxanes William P. D. Goldring and Gerald Pattenden pp 354–361 DOI: 10.1021/ar050186c

Issue 06

Generating Function Methods in Single-Molecule Spectroscopy Frank L. H. Brown pp 363–373 DOI: 10.1021/ar050028l

Nonradical Mechanism for Methane Hydroxylation by Iron-Oxo Complexes Kazunari Yoshizawa pp 375–382 DOI: 10.1021/ar050194t

Switchable Nonlinear Optical Metallochromophores with Pyridinium Electron Acceptor Groups Benjamin J. Coe pp 383–393 DOI: 10.1021/ar050225k

Photophysics and Photochemistry of Pterins in Aqueous Solution Carolina Lorente and Andrés H. Thomas pp 395–402 DOI: 10.1021/ar050151c

Understanding Macroscopic Diffusion of Adsorbed Molecules in Crystalline Nanoporous Materials via Atomistic Simulations David S. Sholl pp 403–411 DOI: 10.1021/ar0402199

Crystalline Molecular Machines:  A Quest Toward Solid-State Dynamics and Function Tinh-Alfredo V. Khuong, Jose E. Nuñez, Carlos E. Godinez, and Miguel A. Garcia-Garibay pp 413–422 DOI: 10.1021/ar0680217

Issue 07

“Host−Guest” Chemistry in the Synthesis of Ordered Nonsiliceous Mesoporous Materials Ying Wan, Haifeng Yang, and Dongyuan Zhao pp 423–432 DOI: 10.1021/ar050091a

Synthesis and Properties of Cyclopropane-Derived Peptidomimetics Andreas Reichelt and Stephen F. Martin pp 433–442 DOI: 10.1021/ar030255s

Surface-Enhanced Raman Scattering in Local Optical Fields of Silver and Gold NanoaggregatesFrom Single-Molecule Raman Spectroscopy to Ultrasensitive Probing in Live Cells Katrin Kneipp, Harald Kneipp, and Janina Kneipp pp 443–450 DOI: 10.1021/ar050107x

Design and Synthesis of New Classes of Heterocyclic C-Glycoconjugates and Carbon-Linked Sugar and Heterocyclic Amino Acids by Asymmetric Multicomponent Reactions (AMCRs) Alessandro Dondoni and Alessandro Massi pp 451–463 DOI: 10.1021/ar068023r

Structural and Molecular Recognition Studies with Acyclic Anion Receptors Philip A. Gale pp 465–475 DOI: 10.1021/ar040237q

Snakes and Ladders. The Sigmatropic Shiftamer Concept Dean J. Tantillo and Roald Hoffmann pp 477–486 DOI: 10.1021/ar0680926

Bioinspired Surfaces with Special Wettability Taolei Sun, Lin Feng, Xuefeng Gao, and Lei Jiang* pp 487–487 DOI: 10.1021/ar068150n

Issue 08

Molecular Organogels. Soft Matter Comprised of Low-Molecular-Mass Organic Gelators and Organic Liquids Mathew George and Richard G. Weiss pp 489–497 DOI: 10.1021/ar0500923

Hydrophobic and Hydrophilic Yoctowells Tianyu Wang, Sheshanath Bhosale, Sidhanath Bhosale, Guangtao Li, and Jürgen-Hinrich Fuhrhop pp 498–508 DOI: 10.1021/ar050129j

Search for Solutions to the Reactivity and Selectivity Problems in Enyne Metathesis Eric C. Hansen and Daesung Lee pp 509–519 DOI: 10.1021/ar050024g

Engaging Zwitterions in Carbon−Carbon and Carbon−Nitrogen Bond-Forming Reactions:  A Promising Synthetic Strategy Vijay Nair, Rajeev S. Menon, A. R. Sreekanth, N. Abhilash, and A. T. Biju pp 520–530 DOI: 10.1021/ar0502026

Probing the Cybotactic Region in Gas-Expanded Liquids (GXLs) Jason P. Hallett, Christopher L. Kitchens, Rigoberto Hernandez, Charles L. Liotta, and Charles A. Eckert pp 531–538 DOI: 10.1021/ar0501424

Applications of Total Synthesis to Problems in Neurodegeneration:  Fascinating Chemistry along the Way Rebecca M. Wilson and Samuel J. Danishefsky pp 539–549 DOI: 10.1021/ar068018n

Domain Relationships in Thiamine Diphosphate-Dependent Enzymes Ronald G. Duggleby pp 550–557 DOI: 10.1021/ar068022z

Correlating Structure with Function in Bacterial Multicomponent Monooxygenases and Related Diiron Proteins Matthew H. Sazinsky and Stephen J. Lippard pp 558–566 DOI: 10.1021/ar030204v

Issue 09

Amyloid FibrilsCommon Threads in the Natural History of Proteins Ronald Wetzel pp 567–567 DOI: 10.1021/ar0681934

The Structural Biology of Protein Aggregation Diseases:  Fundamental Questions and Some Answers David Eisenberg, Rebecca Nelson, Michael R. Sawaya, Melinda Balbirnie, Shilpa Sambashivan, Magdalena I. Ivanova, Anders Ø. Madsen, and Christian Riekel pp 568–575 DOI: 10.1021/ar0500618

Conformational Change and Assembly through Edge β Strands in Transthyretin and Other Amyloid Proteins Janel Laidman, G. Jason Forse, and Todd O. Yeates pp 576–583 DOI: 10.1021/ar050017s

Hydrogen/Deuterium Exchange Mass SpectrometryA Window into Amyloid Structure Indu Kheterpal and Ronald Wetzel pp 584–593 DOI: 10.1021/ar050057w

α-Sheet:  The Toxic Conformer in Amyloid Diseases? Valerie Daggett pp 594–602 DOI: 10.1021/ar0500719

Normal and Aberrant Biological Self-Assembly:  Insights from Studies of Human Lysozyme and Its Amyloidogenic Variants Mireille Dumoulin, Janet R. Kumita, and Christopher M. Dobson pp 603–610 DOI: 10.1021/ar050070g

Small Molecule Oxidation Products Trigger Disease-Associated Protein Misfolding Jan Bieschke, Qinghai Zhang, Daryl A. Bosco, Richard A. Lerner, Evan T. Powers, Paul Wentworth, Jr., and Jeffery W. Kelly pp 611–619 DOI: 10.1021/ar0500766

Sequence and Structural Determinants of Amyloid Fibril Formation Francesco Bemporad, Giulia Calloni, Silvia Campioni, Georgia Plakoutsi, Niccolò Taddei, and Fabrizio Chiti pp 620–627 DOI: 10.1021/ar050067x

The Aggregation and Fibrillation of α-Synuclein Anthony L. Fink pp 628–634 DOI: 10.1021/ar050073t

Elucidating Amyloid β-Protein Folding and Assembly:  A Multidisciplinary Approach David B. Teplow, Noel D. Lazo, Gal Bitan, Summer Bernstein, Thomas Wyttenbach, Michael T. Bowers, Andrij Baumketner, Joan-Emma Shea, Brigita Urbanc, Luis Cruz, Jose Borreguero, and H. Eugene Stanley pp 635–645 DOI: 10.1021/ar050063s

Prions and Transmissible Spongiform Encephalopathy (TSE) Chemotherapeutics:  A Common Mechanism for Anti-TSE Compounds? B. Caughey, W. S. Caughey, D. A. Kocisko, K. S. Lee, J. R. Silveira, and J. D. Morrey pp 646–653 DOI: 10.1021/ar050068p

The Emerging Principles of Mammalian Prion Propagation and Transmissibility Barriers:  Insight from Studies in Vitro Witold K. Surewicz, Eric M. Jones, and Adrian C. Apetri pp 654–662 DOI: 10.1021/ar050226c

Direct Observation of Amyloid Fibril Growth, Propagation, and Adaptation Tadato Ban, Keiichi Yamaguchi, and Yuji Goto pp 663–670 DOI: 10.1021/ar050074l

Kinetics and Thermodynamics of Amyloid Fibril Assembly Ronald Wetzel pp 671–679 DOI: 10.1021/ar050069h

Issue 10

Cooperative Binding and Multiple Recognition by Bridged Bis(β-cyclodextrin)s with Functional Linkers Yu Liu and Yong Chen pp 681–691 DOI: 10.1021/ar0502275

α-C-Galactosylceramides:  Synthesis and Immunology Richard W. Franck and Moriya Tsuji pp 692–701 DOI: 10.1021/ar050006z

Polymer-Induced Flip-Flop in Biomembranes Alexander A. Yaroslavov, Nikolay S. Melik-Nubarov, and Fredric M. Menger pp 702–710 DOI: 10.1021/ar050078q

P-Phos:  A Family of Versatile and Effective Atropisomeric Dipyridylphosphine Ligands in Asymmetric Catalysis Jing Wu and Albert S. C. Chan pp 711–720 DOI: 10.1021/ar0680015

Metallo-β-lactamases:  Novel Weaponry for Antibiotic Resistance in Bacteria Michael W. Crowder, James Spencer, and Alejandro J. Vila pp 721–728 DOI: 10.1021/ar0400241

Modeling Enzymatic Reactions Involving Transition Metals Per E. M. Siegbahn and Tomasz Borowski pp 729–738 DOI: 10.1021/ar050123u

Catalytically Active Gold:  From Nanoparticles to Ultrathin Films Mingshu Chen and D. Wayne Goodman pp 739–746 DOI: 10.1021/ar040309d

Predicting the Stereochemistry of Diphenylphosphino Benzoic Acid (DPPBA)-Based Palladium-Catalyzed Asymmetric Allylic Alkylation Reactions:  A Working Model Barry M. Trost, Michelle R. Machacek, and Aaron Aponick pp 747–760 DOI: 10.1021/ar040063c

Super Radical Stabilizers Xavier Creary pp 761–771 DOI: 10.1021/ar0680724

How Do Low-Energy (0.1−2 eV) Electrons Cause DNA-Strand Breaks? Jack Simons pp 772–779 DOI: 10.1021/ar0680769

Antibodies with Infinite Affinity:  Origins and Applications Nathaniel G. Butlin and Claude F. Meares pp 780–787 DOI: 10.1021/ar020275e

Structural and Electron Paramagnetic Resonance (EPR) Studies of Mononuclear Molybdenum Enzymes from Sulfate-Reducing Bacteria Carlos D. Brondino, María G. Rivas, Maria J. Romão, José J. G. Moura, and Isabel Moura pp 788–796 DOI: 10.1021/ar050104k

Issue 11

Christopher Foote's Discovery of the Role of Singlet Oxygen [1O2 (1Δg)] in Photosensitized Oxidation Reactions Alexander Greer pp 797–804 DOI: 10.1021/ar050191g

Nucleotide Sugar Transporters of the Golgi Apparatus:  From Basic Science to Diseases Carolina E. Caffaro and Carlos B. Hirschberg pp 805–812 DOI: 10.1021/ar0400239

Oxidatively Induced Abstraction Reactions. A Synthetic Approach to Low-Coordinate and Reactive Early Transition Metal Complexes Containing Metal−Ligand Multiple Bonds Daniel J. Mindiola pp 813–821 DOI: 10.1021/ar0500113

Benchmarking State-of-the-Art ab Initio Thermochemical Predictions with Accurate Pulsed-Field Ionization Photoion−Photoelectron Measurements Kai-Chung Lau and Cheuk-Yiu Ng pp 823–829 DOI: 10.1021/ar0402210

Adventures in Drug Discovery:  Potent Agents Based on Ligands for Cell-Surface Receptors Bruce E. Maryanoff pp 831–840 DOI: 10.1021/ar040112l

Synthetic Strategies and Structural Aspects of Metal-Mediated Multiporphyrin Assemblies Elisabetta Iengo, Ennio Zangrando, and Enzo Alessio pp 841–851 DOI: 10.1021/ar040240+

Applications of Planar-Chiral Heterocycles as Ligands in Asymmetric Catalysis Gregory C. Fu pp 853–860 DOI: 10.1021/ar068115g

Excess Electrons Stabilized on Ionic Oxide Surfaces Mario Chiesa, Maria Cristina Paganini, Elio Giamello, Damien M. Murphy, Cristiana Di Valentin, and Gianfranco Pacchioni pp 861–867 DOI: 10.1021/ar068144r

Chemistry of Metal Thio- and Selenocarboxylates:  Precursors for Metal Sulfide/Selenide Materials, Thin Films, and Nanocrystals Jagadese J. Vittal and Meng Tack Ng pp 869–877 DOI: 10.1021/ar050224s

The Emerging Principles of Mammalian Prion Propagation and Transmissibility Barriers:  Insight from Studies in Vitro Witold K. Surewicz, Eric M. Jones, and Adrian C. Apetri pp 879–880 DOI: 10.1021/ar068279x

Issue 12

Some Novel Polymeric Nanocomposites James E. Mark pp 881–888 DOI: 10.1021/ar040062k

Fascination with the Conformational Analysis of Succinic Acid, as Evaluated by NMR Spectroscopy, and Why John D. Roberts pp 889–896 DOI: 10.1021/ar050229p

Ionic-Liquid-Supported Synthesis:  A Novel Liquid-Phase Strategy for Organic Synthesis Weishi Miao and Tak Hang Chan pp 897–908 DOI: 10.1021/ar030252f

“Four-Dimensional” Protein Structures:  Examples from Metalloproteins Marco Fragai, Claudio Luchinat, and Giacomo Parigi pp 909–917 DOI: 10.1021/ar050103s

Reversible Binding of Heme to Proteins in Cellular Signal Transduction Shangwei Hou, Mark F. Reynolds, Frank T. Horrigan, Stefan H. Heinemann, and Toshinori Hoshi pp 918–924 DOI: 10.1021/ar040020w

Peptide Dendrimers as Artificial Enzymes, Receptors, and Drug-Delivery Agents Tamis Darbre and Jean-Louis Reymond pp 925–934 DOI: 10.1021/ar050203y

Synthesis and Biological Properties of Sequence-Specific DNA-Alkylating Pyrrole−Imidazole Polyamides Toshikazu Bando and Hiroshi Sugiyama pp 935–944 DOI: 10.1021/ar030287f

Ground- and Excited-State Tautomerism in Porphycenes Jacek Waluk pp 945–952 DOI: 10.1021/ar0680365

Polymer Chain Dynamics in Solution Probed with a Fluorescence Blob Model Jean Duhamel pp 953–960 DOI: 10.1021/ar068096a